Patch
AssigneeSaitama Daiichi Seiyaku Kabushiki Kaisha
InventorsToshiyuki Takayasu, Ikuhiro Kakubari, Norihiro Shinkai, Junji Kawakami, Noriko Nakajima, Akemi Uruno
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Abstract
A transdermal patch containing a drug comprising formoterol and/or a salt, a solvent for the drug, a pressure-sensitive adhesive comprising an ethylene/vinyl acetate copolymer resin and at least one of a filler and a plasticizer. The patch is substantially water-free. The patch serves to promote percutaneous absorption of the formoterol and/or a salt thereof and allow the efficacy of the drug to stably persist for a long period of time. The patch is thus effective for diseases such as asthma, which can be cured or prevented by exciting β-receptors.
Claims36
A substantially water-free transdermal patch comprising:
- (a) a drug comprising at least one of formoterol and a salt of formoterol,
- (b) 0.1 to 20% by weight based on the weight of the transdermal patch of a solvent for the drug,
- (c) a pressure-sensitive adhesive comprising an ethylene/vinyl acetate copolymer resin, and
- (d) 0.01 to 95% by weight based on the weight of the transdermal patch of at least one of a filler and a plasticizer.
Dependencies are inferred from the claim text.