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US 6,211,337 B1Granted
RIP: novel human protein involved in tumor necrosis factor signal transduction
AssigneeTularik Inc.
InventorsVijay R. Baichwal, Jianing Huang, Hailing Hsu, David V. Goeddel
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Abstract
The invention relates to a human Receptor Interacting Protein (hRIP), nucleic acids which encode hRIP and methods of using the subject compositions; in particular, methods such as hRIP-based in vitro binding assays and phosphorylation assays for screening chemical libraries for lead compounds for pharmacological agents.
Claims24
An isolated RIP-Thr514 polypeptide, comprising at least 10 consecutive amino acid residues of the amino acid sequence set forth as SEQ ID NO:2, which consecutive amino acid residues comprise the amino acid residue 514 (Thr) of SEQ ID NO:2.
Dependencies are inferred from the claim text.