US 6,211,273 B1 · Method for preparing malonate methylidene nanoparticles, nanoparticles optionally containing one or several biologically active molecules

Abstract

The invention relates to a method for the preparation of nanoparticles formed from a random polymer of at least one compound of formula (I) in which A represents a group or a group; R1 and R2, identical or different, represents a linear or branched C1-C6 alkyl group; n=1, 2, 3, 4 or 5, characterised in that the monomer is dissolved beforehand in a water-miscible aprotic organic solvent forming, with the polymerisation medium, a non-solvent mixture of the polymer formed.

Claims22

Dependent claims

A method for the preparation of nanoparticles formed from a random polymer of at least one compound of formula (I)

in which
A represents a
group or a
group;
R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group;
n=1, 2, 3, 4 or 5,
comprising the steps of dissolving said at least one compound of formula (I) in a water-miscible aprotic organic solvent, and mixing the dissolved at least one compound of formula (I) with an aqueous polymerization medium, resulting in a non-solvent mixture of the polymer formed.

4 more elements

Dependencies are inferred from the claim text.

Facts

Application

09/284,455Filed 16 Apr 1999

Priority

FR 96 1303925 Oct 1996

Granted

3 Apr 2001

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 9/5138
Organic macromolecular compounds; Dendrimers: obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone,…
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
A61P 31/10
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antimycotics
A61P 31/12
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antivirals

Method for preparing malonate methylidene nanoparticles, nanoparticles optionally containing one or several biologically active molecules

Life of this patent

Method for preparing malonate methylidene nanoparticles, nanoparticles optionally containing one or several biologically active molecules

Life of this patent

Abstract

Claims22