Rapidly absorbed liquid compositions
AssigneeMcNeil-PPC, Inc.
InventorsCathy Klech Gelotte, Joanna F. Hills, Charles E. Pendley, II, Manoj N. Shah
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Abstract
The present invention provides a method which provides for a faster absorption of pharmaceutically acceptable amines. The method provides a pharmaceutically acceptable amine in combination with a non-steroidal anti-inflammatory drug in a liquid form. A preferred embodiment employs pseudoephedrine and ibuprofen.
Claims37
A method for enhancing the absorption rate of a pharmaceutically acceptable amine into the blood of a human comprising administering a pharmacologically effective dosage of a pharmaceutically acceptable amine and an effective amount of a nonsteroidal anti-inflammatory acidic drug in a stable liquid form.
A composition comprising a pharmacologically effective amount of a pharmaceutically acceptable amine and a pharmacologically effective amount of a nonsteroidal anti-inflammatory drug, wherein said amine and nonsteroidal anti-inflammatory drug are provided in a stable liquid suspension, said suspension comprised of xanthan gum, pregelatinized starch, polyoxyethylene sorbitan monooleate and a taste masking agent selected from the group consisting of sugar, sweet polyhydric alcohol, cyclamates, aspartame, sucralose saccharin, flavoring agents and mixtures thereof, wherein the composition provides an enhanced absorption rate of the amine into the blood of a human compared with a corresponding composition comprising the amine but not the nonsteroidal anti-inflammatory drug.
A stable liquid composition comprising a pharmacologically effective amount of a pharmaceutically acceptable amine and a pharmacologically effective amount of a nonsteroidal anti-inflammatory drug, wherein the composition provides an enhanced absorption rate of the amine into the blood of a human compared with a corresponding composition comprising the amine but not the nonsteroidal anti-inflammatory drug.
Dependencies are inferred from the claim text.