Indole derivatives useful in therapy
AssigneePfizer Inc.
InventorsStephen Challenger, Kevin Neil Dack, Andrew Michael Derrick, Roger Peter Dickinson, David Ellis, Yousef Hajikarimian, Kim James, David James Rawson
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Abstract
The invention provides S-(+)-3-{1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl}-1-methyl-1H-indole-6-carboxylic acid, which is substantially free from its (R)-(−)-enantiomer, and pharmaceutically acceptable derivatives thereof. The compounds are useful in the treatment of inter alia acute renal failure, restenosis and pulmonary hypertension.
Claims16
S-(+)-3-{1-(1,3-Benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl}-1-methyl-1H-indole-6-carboxylic acid, which is substantially free from its (R)-(−)-enantiomer, or a pharmaceutically acceptable derivative thereof.
Dependencies are inferred from the claim text.