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US 6,207,857 B1Granted
Precursor compounds
AssigneeGivaudan Roure (International) SA
InventorsDenise Anderson, Georg Frater
Life of this patent
Estimating the term…
Abstract
The compounds of the formula I are precursors for organoleptic and antimicrobial compounds. The latter are generated in the presence of skin bacteria, enzymes or acidic or alkaline conditions. One precursor molecule can provide one or more different compounds.
Claims17
A compound of the formula I:
- wherein
- R1 is the residue of the enol form of an aldehyde having 7 or more carbon atoms or a ketone having 8 or more carbon atoms,
- X is a saturated bivalent hydrocarbon residue with a straight chain with 1 or 2 carbon atoms or a phenyl ring,
- R2 is a saturated or unsaturated, substituted or unsubstituted carbocyclic or heterocyclic residue or —COOY, wherein Y is a metal atom or R3, and R3 is the residue of an alcohol or phenol or has the same definition as R1 and is the same or different as R1,
- n is 0 or 1,
- wherein if R1 is a 3-phenyl propanal derivative optionally substituted by a methyl group in position 2, the phenyl ring has at least one substituent, and
- if R1 is a 2-phenyl ethanal derivative, the phenyl ring has at least one substituent.
4 more elements
A method for producing one or more organoleptic compounds comprising contacting a compound of formula I:
- with skin bacteria, enzymes, elevated temperature or by acidic or alkaline pH values to cleave the compound of formula I, wherein
- R1 is the residue of the enol form of an aldehyde having 7 or more carbon atoms or a ketone having more than 8 carbon atoms,
- X is a saturated bivalent hydrocarbon residue with a straight chain with 1 or 2 carbon atoms or a phenyl ring,
- R2 is a saturated or unsaturated, substituted or unsubstituted carbocyclic or heterocyclic residue or —COOY, wherein Y is a metal atom or R3, and R3 is the residue of an alcohol or phenol or has the same definition as R1 and is the same or different as R1,
- n is 0 or 1,
- wherein if R1 is a 3-phenyl propanal derivative optionally substituted by a methyl group in position 2, the phenyl ring has at least one substituent, and
- if R1 is a 2-phenyl ethanal derivative, the phenyl ring has at least one substituent.
4 more elements
Dependencies are inferred from the claim text.