Process for preparing 3-isochromanone
AssigneeZeneca Limited
InventorsDavid John Ritchie, Hannah Sallie Robertson McCann, Jennifer Ann White, Kirstin MacCormick, Raymond Vincent Heavon Jones, Robin Fieldhouse
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Abstract
3-Isochromanone is prepared by contacting an o-xylene-α,α′-dihalide with carbon monoxide in a two-phase liquid medium, in which one phase is aqueous and the other phase is water-immiscible, in the presence of a catalyst and a hindered amine base.
Claims11
A process for the preparation of 3-isochromanone which comprises contacting an o-xylene-α,α′-dihalide with carbon monoxide in a two-phase liquid medium, in which one phase is aqueous and the other phase is water-immiscible, in the presence of a catalyst and a hindered amine base.
Dependencies are inferred from the claim text.