Stem cell factor and compositions
AssigneeAmgen Inc.
InventorsKrisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
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Abstract
Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
Claims12
An isolated and purified non-human, mammalian stem cell factor polypeptide possessing hematopoietic biological activity wherein said hematopoietic biological activity is the stimulation of the growth of early hematopoietic progenitor cells, said polypeptide selected from the group consisting of the polypeptides set forth in SEQ ID NOs:
- 50, 51, 52, 53 and 55.
An isolated and purified rat stem cell factor polypeptide having the sequence of SEQ ID NO:
- 42.
Dependencies are inferred from the claim text.