Disposable premoistened wipe containing an antimicrobial protease inhibitor
AssigneeThe Procter & Gamble Company
InventorsFrancis James Rourke, Marc Frederic Richards, Scott Edward Osborne
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Abstract
A disposable wipe which comprises a substrate, an antimicrobial protease inhibitor, and a liquid. The antimicrobial protease inhibitor may be added directly to the substrate and/or added directly to the liquid. The antimicrobial protease inhibitor is capable of inhibiting deleterious fecal microorganisms and protease enzymes thereby aiding in the prevention of diaper dermatitis. The wipe may optionally include other ingredients examples of which include humectants, emollients, surfactants, fragrances, emulsifiers, and preservatives.
Claims4
A premoistened wipe comprising:
- a nonwoven fibrous substrate including from about 0.5 grams to 8 grams of liquid per gram of dry fiber in said substrate and from about 0.004% to 10% antimicrobial protease inhibitor by weight of dry fiber in said substrate wherein said antimicrobial protease inhibitor is an aromatic diamidine, said aromatic diamidine having the formula:
- wherein X is H or OH, and
- wherein n=3 to 12 and X is Cl, I, Br, F or H
- wherein said aromatic diamidine is hexamidine diisethionate.
A premoistened wipe comprising:
- a nonwoven fibrous substrate including from about 0.5 grams to 8 grams of liquid per gram of dry fiber said liquid further comprising:
- a) a solvent comprising at least about 50% of said liquid by weight, said solvent selected from the group consisting of oil, alcohol, water, and mixtures thereof;
- and
- b) at least one Antimicrobial protease inhibitor comprising from about 0.0005% to 10% of said liquid by weight wherein said antimicrobial protease inhibitor is an aromatic diamidine said aromatic diamidine having the formula:
- wherein X is H or OH, and
- wherein n=3 to 12 and X is Cl, I, Br, F or H
- wherein said aromatic diamidine is hexamidine diisethionate.
Dependencies are inferred from the claim text.