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US 6,207,453 B1Granted
Recombinant AAV vector-based transduction system and use of same
AssigneeMediGene AG
InventorsGerd Maass, Christoph Bogedain, Michael Hallek, Clemens Wendtner, Doris Michl
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Abstract
The present invention relates to a transduction system, comprising (a) a rep-negative AAV vector containing a foreign DNA and (b) a product providing an AAV Rep protein. The invention also relates to the use of the transduction system.
Claims13
A transduction system comprising
- (a) a rep-negative adeno-associated virus (AAV) vector containing a foreign DNA;
- and
- (b) a product providing an AAV Rep protein wherein the AAV vector is bound to the product, wherein said product is a DNA molecule.
Dependencies are inferred from the claim text.