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US 6,207,366 B1Granted
Chronic fatigue syndrome diagnosis
AssigneeTemple University of the Commonwealth System of Higher Education
InventorRobert J. Suhadolnik
Life of this patent
Estimating the term…
Abstract
Chronic fatigue syndrome is diagnosed through quantification of low and high molecular weight forms of RNase L in cellular extracts of RNase L-containing cells such as peripheral blood mononuclear cells. A ratio of low to high molecular weight RNase L of more than 0.15 is characteristic of chronic fatigue syndrome.
Claims15
A method for diagnosing chronic fatigue syndrome comprising
- determining the level of low molecular weight RNase L and the level of high molecular weight RNase L in a biological sample from a human subject;
- and
- computing a ratio for the level of low molecular weight RNase L to the level of high molecular weight RNase L in the sample, which ratio is diagnostic for chronic fatigue syndrome.
Dependencies are inferred from the claim text.