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US 6,207,172 B1Granted
Composition for the delivery of a pharmaceutical agent to a patient
AssigneeWarner-Lambert Company
InventorsHoward Yoshihisa Ando, Steven Edward Rose
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Abstract
The present invention relates to a composition for the delivery of a pharmaceutical agent to a patient that comprises polyethylene glycol, an aqueous solution containing polyvinylpyrrolidone, and a pharmaceutical agent. The invention also relates to methods of making a composition for the delivery of a pharmaceutical agent.
Claims12
A liquid composition for the delivery of a pharmaceutical agent to a patient, the composition comprising:
- a. polyethylene glycol having a weight-average molecular weight in the range of about 1,300 to about 9,000;
- b. an aqueous solution containing from about 5% (w/v) to about 20% (w/v) polyvinylpyrrolidone with respect to the entire solution, the polyvinylpyrrolidone having a weight-average molecular weight in the range of about 2,000 to about 30,000;
- c. a biologically compatible buffer having a pH of about 1.0 to about 7.4;
- and
- d. a pharmaceutical agent selected from N4-(3-Bromo-phenyl-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine or Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-ethyl-amine.
2 more elements
Dependencies are inferred from the claim text.