Polyphosphazene microspheres
AssigneeAvant Immunotherapeutics, Inc.
InventorsLendon G. Payne, Angela L. Woods, Sharon A. Jenkins
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Abstract
A soluble polyphosphazene polyelectrolyte immunoadjuvant is disclosed. In one embodiment, the polymeric adjuvant is poly[di(carboxylatrophenoxy)phosphazene] which is in the form of a microsphere and which is adsorbed with antigen after formation of the microsphere. The immunoadjuvant can be administered intranasally.
Claims5
A method for producing an immune response in an animal comprising administering to the animal an antigen and a polyphosphazene polyelectrolyte microparticle in an amount effective to elicit an immune response, wherein the antigen has been adsorbed onto the microparticle surface.
A composition for producing an immune response in an animal comprising a polyphosphazene microparticle and an antigen adsorbed on the microparticle surface in an amount effective to elicit an immune response.
Dependencies are inferred from the claim text.