Patient-specific white blood cell malignancy vaccine from membrane-proteoliposomes
AssigneeBiomira USA Inc.
InventorsMircea C. Popescu, Lawrence Boni, Richard J. Robb, Michael M. Batenjany
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Abstract
Membrane-proteoliposome structures (MPs) are useful in preparing patient-specific vaccines against specific white blood cell (WBC) malignancies. The inventive MPs typically contain a membrane component derived from a specific WBC. Other useful components include immunostimulators and exogenous lipids. The resulting vaccines are both patient- and malignancy-specific.
Claims21
A patient-specific vaccine for treating white blood cell malignancy, comprising a membrane-proteoliposome (MP) containing plasma membrane from a malignant white blood cell.
A membrane-proteoliposome (MP), comprising integral membrane from a malignant white blood cell, at least one immunostimulator and an exogenous lipid.
Dependencies are inferred from the claim text.