Process for the preparation of a stable, homogeneous, extract free or nearly free from secondary reaction products

A process for the preparation of a stable, homogeneous extract of plants or parts thereof,

• comprising mixing plants or plant parts charged in a fresh and/or dried state with at least one solvent and at least one agent and extracting the plants or plant parts with the solvent and agent, and thereafter filtering insoluble compounds so as to obtain a filtrate,
• wherein said filtrate is substantially free of secondary reaction products and contains a native compound mixture;
• and wherein said agent:
• (i) increases the solubility of at least one extracted compound contained in the filtrate;
• (ii) increases the viscosity of the filtrate in the presence of the solvent(s);
• (iii) decreases the steam pressure of volatile extracted compounds contained in the filtrate;
• (iv) prevents or reduces the chemical and/or enzymatic reactions between one or more extracted compounds contained in the filtrate;
• (v) prevents or reduces the sedimentation and/or flotation of extracted compounds contained in the filtrate when the filtrate is in liquid or semisolid form or is dissolved and/or suspended and/or emulsified in at least one solvent;
• and
• (iv) increases the stability and/or homogeneity of at least one extracted compounds contained in the filtrate,
• wherein said filtrate is concentrated to a spissum extract and the pressure used for the concentration is adjusted according to the vapor pressure of the solvent(s), and optionally the spissum extract is dried to obtain a dry extract which is in a solid state of aggregation at a temperature below 60° C., or the spissum extract is mixed with at least one pharmaceutically acceptable solvent so that a preparation is obtained which is in a liquid state of aggregation at a temperature of below 50° C.