Differential treatment of prosthetic devices
AssigneeSt. Jude Medical, Inc.
InventorsR. Brian Williams, Richard F. Schroeder, Matthew F. Ogle
Life of this patent
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Abstract
An apparatus is disclosed for differentially treating a medical device. One portion of the device is treated with a first fluid and a separate portion is treated with a second fluid. The second fluid generally is substantially different from the first fluid. The first fluid can be contacted with an flow region of the medical device. The apparatus can include a conduit system, where fluid flowing through the conduit system flows through the flow region. Sheet material can be treated differentially on the opposite surfaces of the sheet. The medical device can include vascular tissue.
Claims18
A prosthetic device comprising tissue separate from an organism, said tissue comprising a first portion having a surface with a chemical modification and a second portion isolated from said first portion having a surface structure that is substantially devoid of said chemical modification, said chemical modification being selected from the group consisting of an associated calcification inhibiting composition, an associated antimicrobial composition, decellularization, an associated growth factor and an assciated cell adhesion compound, wherein the calcification inhibiting composition is selected from the group consisting of alcohols, toluidine blue, diphosphates, detergents, alpha amino oleic acid and polyvalent metal ions.
A prosthetic device comprising tissue, said tissue having a first portion chemically crosslinked with a first crosslinking agent and a second portion isolated from said first portion, said second portion being chemically crosslinked with a second crosslinking agent and not crosslinked by said first crosslinking agent, wherein said first portion is not crosslinked with said second crosslinking agent.
Dependencies are inferred from the claim text.