Multiple sequence alignment system and method
AssigneeInternational Business Machines Corporation
InventorsAris Floratos, Laxmi P. Parida, Isidore Rigoutsos
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AssigneeInternational Business Machines Corporation
InventorsAris Floratos, Laxmi P. Parida, Isidore Rigoutsos
Estimating the term…
The method of the present invention aligns a set of N sequences, where N is large. The alignment brings out the best commonality of the N sequences. The method is performed in two stages. A first stage involving discovering motifs, and a second stage involve motif pruning and sequence alignment. The present invention also provides an additional constraint, K, as a user defined control parameter. The additional parameter constrains the alignment of the N sequences to have at least K of the N sequences agree on a character, whenever possible, in the alignment. The alignment number, K, provides a natural constraint for dealing with a large number of sequences in that a commonality across most, if not all sequences is required to be detected.
A method for aligning characters in character sequences, said method steps comprising:
A method for aligning characters in character sequences, said method steps comprising:
A computer program device readable by a machine, tangibly embodying a program of instructions executable by the machine to perform method steps for aligning characters in character sequences, said method steps comprising:
Dependencies are inferred from the claim text.