Water soluble fullerenes with antiviral activity
AssigneeThe Regents of the University of California
InventorsSimon H. Friedman, Raymond F. Schinazi, Fred Wudl, Craig L. Hill, Diane L. DeCamp, Rintje P. Sijbesma, George L. Kenyon
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Abstract
A water soluble derivative of buckministerfullerene (C60) having antiviral and virucidal properties is used to inhibit human retroviral replication and infections. The derivatized fullerene is symmetrically substituted with polar organic moieties containing 1 to 20 carbon atoms and optionally further containing oxygen or nitrogen.
Claims15
A compound selected from the group consisting of a water soluble derivative of buckministerfullerene (C60) having virucidal properties and water soluble salts thereof, wherein the buckminsterfullerene is a methanofullerene.
Dependencies are inferred from the claim text.