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US 6,204,374 B1Granted
Cell cycle regulatory gene
AssigneeThe Johns Hopkins University School of Medicine
InventorDavid Sidransky
Life of this patent
Estimating the term…
Abstract
A novel cell cycle regulatory gene called 5′ALT is disclosed. Methods for determining mutations or polymorphisms in 5′ALT or 5′ALT regulated genes in tissues are also provided. Novel 5′ALT-p16 and 5′ALT-p15 transcripts and truncated expression products are also described.
Claims2
Isolated oligonucleotide primer pairs “for diagnosis of a subject having or at risk of having a cell proliferative disorder” which specifically hybridize with target polynucleotide sequences having a polynucleotide sequence as set forth in SEQ ID NO:14 and SEQ ID NO:15.
Dependencies are inferred from the claim text.