Retro-inverso thymosin alpha 1 hybrids
AssigneeUSA Universe Bioengineering, Inc.
InventorDanny Zhong Der Pang
Life of this patent
Estimating the term…
Abstract
Retro-inverso thymosin alpha 1 and its hybrids, native/retro-inverso thymosin alpha 1, possess the characteristics of greater stability and activity than their parent thymosin alpha 1. Such novel analogs and hybrids are useful for therapeutic purposes in viral, neoplastic and immunodeficiency diseases.
Claims2
A peptide having an amino acid sequence (SEQ ID NO:2) of Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser—Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn—Asn-Glu-Ala-Glu-Glu-Val-Val-Glu-Lys-Lys-Glu-Lys-Leu-Asp-Lys-Thr-Thr-Ile-Glu-Ser—Ser-Thr-Asp-Val-Ala-Ala-Asp-Ser in all-D, all-L, or partial D configuration.
A peptide having an amino acid sequence (SEQ ID NO:1) of Asn-Glu-Ala-Glu-Glu-Val-Val-Glu-Lys—Lys-Glu-Lys-Leu-Asp-Lys-Tbr-Thr-Ile-Glu-Ser-Ser-Thr-Asp-Val-Ala-Ala-Asp-Ser in all-D or all-L configuration.
Dependencies are inferred from the claim text.