Antioxidant compounds
AssigneeOrion Corporation
InventorsMarkku Ahotupa, Lauri Kangas
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Abstract
A new use of halogenated triphenylethylene derivatives for lowering levels of serum lipid peroxides and for the prevention or treatment of oxidative tissue damage induced by lipid peroxidation is disclosed. The new use includes the prevention or treatment of artherosclerosis, ischemic injury, psoriasis, inflammatory diseases, such as inflammatory bowel disease, or cardiovascular disorders, such as coronary heart disease, cardiac ischemic injury and post-ischemic cardiac arrhythmias, or the treatment of AIDS.
Claims6
A method of therapy involving protection of organs from oxidative damage induced by lipid peroxidation comprising administering to a subject in need of such therapy an effective amount of a compound of formula (I)
- or a pharmaceutically acceptable salt thereof.
A method of therapy for treating a condition involving inhibiting the production of reactive oxygen species by activated neutrophils comprising administering to a subject in need of such therapy an effective amount of a compound of formula (I)
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.