Analgesic composition and method for using same
AssigneeSolvay Pharmaceuticals GmbH
InventorsCarolyn A. Fairbanks, George L. Wilcox, Laura S. Stone, Kelley F. Kitto
Life of this patent
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Abstract
A pharmaceutical analgesic composition comprise an opioid analgesic agent and moxonidine as a non-opioid agent with analgesic activity. Administration of an opioid analgesic agent and moxonidine as a non-opioid agent produces analgesia in the treatment of pain in mammals.
Claims6
A pharmaceutical analgesic composition, comprising synergistically analgesic effective amounts of:
- moxonidine or a pharmaceutically acceptable salt thereof;
- and
- an opioid analgesic agent selected from the group consisting of morphine and deltorphin or a pharmaceutically acceptable derivative or salt thereof.
A method for producing analgesia in a larger mammal comprising:
- co-administering synergistically analgesic effective amounts of moxonidine or a pharmaceutically acceptable salt thereof and an opioid analgesic agent selected from the group consisting of morphine and deltorphin or a pharmaceutically acceptable derivative or salt thereof.
A method for producing a pharmaceutical analgesic composition comprising combining synergistically analgesic effective amounts of:
- moxonidine or a pharmaceutically acceptable salt thereof;
- and
- an opioid analgesic agent selected from the group consisting of morphine and deltorphin or a pharmaceutically acceptable derivative or salt thereof.
A pharmaceutically analgesic composition in the form of an intrathecally injectable solution, comprising synergistically analgesic effective amounts of:
- 0.1 to 3 mg moxonidine or a pharmaceutically acceptable salt thereof per single unit dosage;
- and
- 1 to 3.3 mg of an opioid analgesic agent selected from the group consisting of morphine and deltorphin or a pharmaceutically acceptable derivative or salt thereof,
- wherein the moxonidine and opioid analgesic agent are in a single solution or in separate solutions.
Dependencies are inferred from the claim text.