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US 6,203,808 B1Granted
Ceramide compounds, process of preparation and use
AssigneeL'oreal
InventorsRémy Tuloup, Michel Philippe
Life of this patent
Estimating the term…
Abstract
The present application relates to novel ceramide compounds to their process of preparation and to their use in cosmetics or in pharmaceuticals, in particular for treating and caring for the skin, hair, nails and eyelashes.
Claims12
An aqueous dispersion of lipid spherules comprising organized molecular layers enclosing an encapsulated aqueous phase, said layers comprising at least one compound of formula (I) in combination with at least one lipid compound, said at least one lipid compound differing from said at least one compound of formula (I), said compound of formula (I) having the following structure:
- R1—CH(OH)—CH(CH2OH)—NH—CO—NR2R3 (I)
- in which:
- R1 is chosen from saturated and unsaturated, linear and branched, C9 to C23 alkyl radicals which may be optionally hydroxylated,
- R2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C1 to C8 alkyl radicals, and
- R3 is chosen from saturated and unsaturated, linear and branched, C1 to C32 alkyl radicals which may be optionally substituted with at least one hydroxyl radical, wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C1 to C24 acyl radicals;
- R3 can optionally be interrupted by 1 to 7 heteroatoms.
3 more elements
A composition comprising:
- (a) at least one compound of formula (I):
- R1—CH(OH)—CH(CH2OH)—NH—CO—NR2R3 (I)
- in which:
- R1 is chosen from saturated and unsaturated, linear and branched, C9 to C23 alkyl radicals which may be optionally hydroxylated;
- R2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C1 to C8 alkyl radicals;
- and
- R3 is chosen from saturated and unsaturated, linear and branched, C1 to C32 alkyl radicals which may be optionally substituted with at least one hydroxyl radical, wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C1 to C24 acyl radicals;
- R3 can optionally be interrupted by 1 to 7 heteroatoms;
- (b) at least one aqueous dispersion of lipid spherules comprising organized molecular layers enclosing an encapsulated aqueous phase, said layers comprising at least one compound of formula (I) in combination with at least one lipid compound, said at least one lipid compound differing from said at least one compound of formula (I);
- or
- (c) a mixture of said at least one compound of formula (I) and said at least one aqueous dispersion.
8 more elements
A moisturizing, emollient and/or softening agent comprising:
- (a) a compound of formula (I):
- R1—CH(OH)—CH(CH2OH)—NH—CO—NR2R3 (I)
- in which:
- R1 is chosen from saturated and unsaturated, linear and branched, C9 to C23 alkyl radicals which may be optionally hydroxylated,
- R2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C1 to C8 alkyl radicals, and
- R3 is chosen from saturated and unsaturated, linear and branched, C1 to C32 alkyl radicals which may be optionally substituted with at least one hydroxyl radical, wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C1 to C24 acyl radicals;
- R3 can optionally be interrupted by 1 to 7 heteroatoms;
- or
- (b) at least one aqueous dispersion of lipid spherules comprising organized molecular layers enclosing an encapsulated aqueous phase, said layers comprising at least one compound of formula (I) in combination with at least one lipid compound, said at least one lipid compound differing from said at least one compound of formula (I).
6 more elements
A moisturizing, emollient and/or softening agent comprising
- (a) a compound of formula (I):
- R1—CH(OH)—CH(CH2OH)—NH—CO—NR2R3 (I)
- in which:
- R1 is chosen from saturated and unsaturated, linear and branched, C9 to C23 alkyl radicals which may be optionally hydroxylated,
- R2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C1 to C8 alkyl radicals, and
- R3 is chosen from saturated and unsaturated, linear and branched, C1 to C32 alkyl radicals which may be optionally substitute with at least one hydroxyl radical, wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C1 to C24 acyl radicals;
- R3 can optionally be interrupted by 1 to 7 heteroatoms;
- and
- (b) at least one aqueous dispersion of lipid spherules comprising organized molecular layers enclosing an encapsulated aqueous phase, said layers comprising at least one compound of formula (I) in combination with at least one lipid compound, said at least one lipid compound differing from said at least one compound of formula (I).
6 more elements
A method for forming lipid spherules comprising:
- combining at least one compound of formula (I) with at least one lipid compound under conditions sufficient to form said lipid spherules,
- said at least one lipid compound differing from said at least one compound of formula (I), and
- said compound of formula (I) having the following structure:
- R1—CH(OH)—CH(CH2OH)—NH—CO—NR2R3 (I)
- in which:
- R1 is chosen from saturated and unsaturated, linear and branched, C9 to C23 alkyl radicals which may be optionally hydroxylated,
- R2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C1 to C8 alkyl radicals, and
- R3 is chosen from saturated and unsaturated, linear and branched, C1 to C32 alkyl radicals which may be optionally substituted with at least one hydroxyl radical,
- wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C1 to C24 acyl radicals;
- R3 can optionally be interrupted by 1 to 7 heteroatoms.
7 more elements
Dependencies are inferred from the claim text.