Method of contrast enhanced magnetic resonance imaging using carbohydrate particles
AssigneeNycomed Imaging AS
InventorUlf Schröder
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Abstract
In a method of contrast MR imaging, using parenterally administered contrast agents, the improvement comprising using as the contrast agent, e.g. to achieve a negative contrast effect, composite particles comprising a biotolerable, carbohydrate or carbohydrate derivative, preferably polymeric, matrix material containing magnetically responsive particles, eg. of magnetite.
Claims9
In a method of contrast enhanced nuclear magnetic resonance diagnostic imaging which comprises administering into the vascular system of a subject a contrast enhancing amount of a nuclear magnetic resonance imaging contrast agent and generating an image of said subject, the improvement comprising administering as said contrast agent composite particles comprising a biotolerable, biodegradable, non-immunogenic carbohydrate or carbohydrate derivative matrix material containing magnetically responsive particles, said magnetically responsive particles being of a material having a Curie temperature and said composite particles being no larger than one micrometer in size.
Dependencies are inferred from the claim text.