Method of making biodegradable implant material and products made therefrom
AssigneeOsteoBiologics, Inc.
InventorsMary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
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Abstract
This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
Claims18
A composition suitable for hand-shaping for use as a tissue implant comprising a molded biodegradable, porous polymeric implant material having a Poisson's ratio at room temperature less than about 0.3, a porosity between about 60 volume percent and about 90 volume percent, wherein the pore size distribution throughout the material is substantially uniform, said implant material being molded into a shape having an aspect ratio of about 3 or more, wherein said molded implant material is hand-shapable at a temperature of about 45° C. to about 50° C. without loss of structural integrity.
A method of implanting a biodegradable polymeric material having uniform pores for selected tissue ingrowth into a defect in a patient's body comprising:
- a) selecting a biodegradable polymeric implant composed of a material having a Poisson's ratio less than about 0.3;
- b) hand-shaping said material to fit said defect at a temperature of about 45° C. to about 50° C.;
- c) placing said material into said defect prior to, or after, hand-shaping said material.
Dependencies are inferred from the claim text.