Pharmaceutical compositions containing chondroitinase and uses therefor
OwnerJ. Thomas Lamont, K. Ramakrishnan Bhaskar +1inventors
InventorsJ. Thomas Lamont, K. Ramakrishnan Bhaskar, Allan M. Green
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Abstract
Gastrointestinal mucus from patients suffering from cystic fibrosis has been found to contain large amounts of chondroitin sulfate polymer. This finding indicates that the enzyme chondroitinase is useful for preventing gastrointestinal mucus from accumulating in cystic fibrosis patients, and subjects suffering from other diseases or conditions characterized by excess mucus secretion.
Claims6
A method for treating a subject having a disorder characterized by the accumulation of mucoid secretions, comprising administering to the subject a therapeutically effective amount of an agent that prevents chondroitin sulfate accumulation such that treatment of the subject occurs, wherein the agent is a chondroitinase enzyme.
Dependencies are inferred from the claim text.