Hypodermic needle for percutaneous drug delivery
AssigneeAdvanced Research and Technology Institute, Inc.
InventorMatthew S. Johnson
Life of this patent
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Abstract
Devices and methods are disclosed for the percutaneous administration of a composition to a desired in vivo location. The composition comprises a biologically active substance and a pharmaceutically acceptable carrier. The pharmaceutically acceptable carrier is preferably non-solid and a polymer, which is preferably capable of being transformed into a gel, thus allowing timed-released delivery of the substance. A preferred use for this invention is to provide local delivery of biologically active substances for the prevention of restenosis following angioplasty or other blood vessel injury.
Claims8
A hypodermic needle for percutaneously delivering desired biologically active substances, the needle comprising a tubular member having a selected radius, the tubular member comprising:
- (a) at least two lumens therethrough,
- (b) a first section which lies along a longitudinal axis of the tubular member, and
- (c) a second section fluidly connected to the first section;
- the second section lying substantially along an arc and terminating in a piercing part located off of the longitudinal axis which includes at least one lumen opening therein.
A hypodermic needle for percutaneously delivering at least two compositions simultaneously, the needle including a tubular member comprising:
- (a) a first lumen capable of delivering a first composition;
- (b) a second lumen capable of delivering a second composition;
- (c) at least one lumen opening fluidly connected to the first and second lumens for outputting the compositions from the device;
- (d) a piercing part;
- and
- (e) a hub that includes (i) a first receiving portion that selectively permits inputting the first composition into the first lumen, (ii) a second receiving portion for selectively inputting the second composition into the second lumen, and (iii) a head portion, wherein the first receivingportion extends substantially vertically from the head portion and wherein the second receiving portion extends substantially horizontally from the head portion.
A hypodermic needle for percutaneously delivering desired biologically active substances, the needle including a tubular member comprising:
- (a) an outer wall defining an internal cavity;
- and
- (b) a partition dividing the internal cavity of said tubular member into two separate lumens, wherein the tubular member includes a first section which lies along a longitudinal axis of the tubular member, and a second section fluidly connected to the first section, and wherein the second section lies substantially along an arc and terminates in a piercing part located off of the longitudinal axis which includes at least one lumen opening therein.
Dependencies are inferred from the claim text.