In-vivo apparatus and methods of use for determining the effects of materials, conditions, activities, and lifestyles on blood parameters
AssigneeVisco Technologies, Inc.
InventorKenneth Kensey
Life of this patent
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AssigneeVisco Technologies, Inc.
InventorKenneth Kensey
Estimating the term…
A blood viscosity measuring system and method that monitors the rising head of a column of fluid representing a living being's blood in-vivo to determine the blood viscosity over a range of shears. The system includes a capillary tube, at least a portion of which is located within the vascular system of the being, and a riser tube, having a liquid therein coupled to the capillary tube. A sensor and associated microprocessor are provided to determine the change in the height of the liquid in the riser tube at plural points along the length of the tube from which the viscosity is calculated. The system can be utilized to determine the deformability of the red blood cells of a living being's blood and/or the thixotropic properties of a living being's blood. Use of the system enables one to screen a material, e.g., a pharmaceutical, on a test subject, such as a living human being or laboratory animal, to determine the likely effect of the material in altering a parameter of the blood, e.g., viscosity, red blood cell deformability, or thixotropic nature, of a living, e.g., human, being to which the material will ultimately be administered.
A method of screening a material to determine its effect in altering the deformability of red blood cells in the blood of a living being, comprising the step of introducing the material into the body of the living being, and utilizing an in-vivo measuring instrument to determine the likely effect of said material on the deformability of red blood cells of the being's blood.
A method of screening a material to determine its effect in altering the thixotropic properties of the blood of a living being, comprising the step of introducing the material into the body of the living being, and utilizing an in-vivo measuring instrument to determine the likely effect of said material on the thixotropic properties of the living being's blood.
A method of determine determining the effect of a condition, activity, and/or lifestyle on the viscosity of the blood of a living being, comprising the step of selecting the living being exhibiting said condition, activity, and/or lifestyle, and utilizing an in-vivo viscosity measuring instrument to determine the likely effect of said condition, activity, and/or lifestyle on the viscosity of the blood of the living being.
A method of determining the effect of a condition, activity, and/or lifestyle on the deformability of red blood cells in the blood of a living being, comprising the step of selecting the living being exhibiting said condition, activity, and/or lifestyle, and utilizing an in-vivo viscosity measuring instrument to determine the likely effect of said condition, activity, and/or lifestyle on the deformability of red blood cells in the blood of the living being.
A method of determining the effect of a condition, activity, and/or lifestyle on the thixotropic properties of the blood of a living being, comprising the step of selecting the living being exhibiting said condition, activity, and/or lifestyle, and utilizing an in-vivo viscosity measuring instrument to determine the likely effect of said condition, activity, and/or lifestyle on the thixotropic properties of the blood of the living being.
Dependencies are inferred from the claim text.