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US 6,199,607 B1Granted
Formulation for inhalation
AssigneeAstra Aktiebolag
InventorJan Trofast
Life of this patent
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Abstract
A dry powder composition comprising formoterol and a carrier substance, both of which are in finely divided form, wherein the formulation has a poured bulk density of from 0.28 to 0.38 g/ml is useful in the treatment of respiratory disorders.
Claims13
A dry powder composition comprising
- (a) an active substance selected from the group consisting of formoterol, pharmaceutically acceptable salts of formoterol, solvates of formoterol, and solvates of formoterol, and
- (b) a carrier substance selected from the group consisting of monosaccharides, disaccharides, polysaccharides and sugar alcohols,
- wherein both the active substance and the carrier substance are in finely divided form, and the composition has a poured bulk density of from 0.28 to 0.38 g/ml is substantially agglomerated, and is suitable for inhalation.
A dry powder composition comprising
- (a) an active substance selected from the group consisting of formoterol, pharmaceutically acceptable salts of formoterol, solvates of formoterol, and solvates of formoterol salts, and
- (b) a carrier substance,
- wherein both the active substance and the carrier substance have a mass median diameter of less than 10 μm, and the composition has a poured bulk density of from 0.28 to 0.38 g/ml, is substantially agglomerated, and is suitable for inhalation.
Dependencies are inferred from the claim text.