Ama
AssigneesThe Brigham and Women's Hospital, Inc., Virus Research Institute, SmithKline Beecham Corporation
InventorsRichard O Nicholas, Leslie Marie Palmer, Julie M Pratt, David T. Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson
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Abstract
This invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
Claims9
An isolated polynucleotide segment comprising a nucleic acid sequence that encodes a polypeptide comprising the amino acid sequence of SEQ ID NO:2, wherein the nucleic acid sequence is not genomic DNA.
An isolated polynucleotide segment comprising a nucleic acid sequence of SEQ ID NO:1, wherein the nucleic acid sequence is not genomic DNA.
An isolated polynucleotide segment comprising a nucleic acid sequence that is fully complementary to a reference polynucleotide that encodes a polypeptide comprising the amino acid sequence of SEQ ID NO:
- 2, wherein the nucleic acid sequence is not genomic DNA.
An isolated polynucleotide segment comprising a nucleic acid sequence that is fully complementary to the reference polynucleotide of SEQ ID NO:1, wherein the nucleic acid sequence is not genomic DNA.
Dependencies are inferred from the claim text.