Broad spectrum microbicidal and spermicidal compositions and methods having activity against sexually transmitted agents including papillomaviruses
AssigneeThe Pennsylvania State University
InventorsMary K. Howett, John W. Kreider
Life of this patent
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Abstract
Microbicidal and spermicidal methods and topical pharmaceutical compositions containing sodium dodecyl sulfate or its derivatives as active ingredients for the prevention and control of pregnancy and sexually transmitted diseases, including human papilloma viruses. Spermicidal barriers and microbial disinfectants containing the compositions are also provided.
Claims15
A microbicidal composition, comprising a compound selected from the group consisting of sodium dodecyl sulfate, lithium dodecyl sulfate, lauric acid or a pharmaceutically acceptable salt thereof in a sufficient amount to attain a virucidal effect against a non-enveloped virus, and a pharmaceutically acceptable carrier.
A method for preventing pregnancy and sexually transmitted disease, comprising the steps of providing a topical composition containing a sufficient amount of a compound selected from the group consisting of sodium dodecyl sulfate, lithium dodecyl sulfate, lauric acid or a pharmaceutically acceptable salt thereof, to attain a spermicidal effect and a virucidal effect against a non-enveloped virus.
A barrier for preventing pregnancy and sexually transmitted disease, wherein said barrier comprises a substrate and a compound selected from the group consisting of sodium dodecyl sulfate, lithium dodecyl sulfate, lauric acid or a pharmaceutically acceptable salt thereof on said substrate in a sufficient amount of a topical composition to attain a spermicidal effect and a virucidal effect against a non-enveloped virus.
A composition for killing papillomaviruses, comprising a virucidal agent consisting essentially of an anionic surfactant wherein said surfactant is selected from the group consisting of sodium dodecyl sulfate, lithium dodecyl sulfate, lauric acid or pharmaceutically acceptable salt thereof in an amount sufficient to attain a virucidal effect against papillomaviruses.
Dependencies are inferred from the claim text.