Process for the manufacture of dihydrocitral
AssigneeRoche Vitamins Inc.
InventorWerner Bonrath
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Abstract
A process for the manufacture of dihydrocitral, a valuable intermediate, through the catalyzed rearrangement of dihydrodehydrolinalool by carrying out the rearrangement in the presence of a molybdenum compound of the general formula MoO2X2 wherein X signifies an acetylacetonate or halide ion, and a dialkyl or diaryl sulphoxide as the catalyst system, in the presence of an organic acid having a pK value in the range of about 4.0 to about 6.5 and in an aprotic organic solvent.
Claims22
A process for the manufacture of dihydrocitral by the catalytic rearrangement of dihydrodehydrolinalool to dihydrocitral, which process comprises carrying out the rearrangement of dihydrodehydrolinalool in the presence of a molybdenum compound of the general formula MoO2X2 wherein X is an acetylacetonate or a halide ion, a sulphoxide which is selected from the group consisting of dialkyl sulphoxides and diaryl sulphoxides and an organic acid having, a pK value from about 4.0 to about 6.5, in an aprotic organic solvent to provide dihydrocitral.
A process for the manufacture of dihydrocitral by the catalytic rearrangement of dihydrodehydrolinalool to dihydrocitral, comprising:
- (a) mixing dihydrodehydrolinalool, a molybdenum compound of the general formula MoO2X2 wherein X is an acetylacetonate or halide ion, a dialkyl or diaryl sulphoxide, and an organic acid having a pK value of from about 4.0 to about 6.5 and an aprotic organic solvent, to provide a reaction mixture;
- (b) heating the reaction mixture to a temperature at which the catalytic rearrangement reaction occurs, to provide a resulting mixture;
- and
- (c) obtaining the dihydrocitral from the resulting mixture.
Dependencies are inferred from the claim text.