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US 6,191,262 B1Granted
Contrast agent preparation
AssigneeNycomed Imaging AS
InventorsOle Homestad, Espen Myrbraten
Life of this patent
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Abstract
In the metallation of complexing agents such as DTPA-BMA with a lanthanide using a lanthanide oxide such as the lanthanide source, oxalic acid is used as a reaction accelerator.
Claims13
A process for the preparation of a lanthanide complex by reaction of a lanthanide oxide with a complexing agent in an aqueous reaction medium, wherein oxalic acid or a salt thereof is used as a reaction accelerator.
Dependencies are inferred from the claim text.