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US 6,191,261 B1Granted
Growth differentiation factor-9 antibodies and methods
AssigneeThe Johns Hopkins University School of Medicine
InventorSe-Jin Lee
Life of this patent
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Abstract
Growth differentiation factor-9 (GDF-9) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-9 polypeptide and polynucleotide sequences.
Claims9
An antibody that specifically binds to a growth differentiation factor-9 (GDF-9) polypeptide of SEQ ID NOS:
- 4 or 26, or binds to antigenic fragments thereof.
A method of detecting or quantifying the levels of a GDF-9 polypeptide having the sequence of SEQ ID NOs:
- 4 or 26 in a sample comprising contacting a sample with an antibody that specifically binds to growth differentiation factor-9 (GDF-9) polypeptide of SEQ ID NOS:
- 4 or 26, or binds to antigenic fragments thereof and detecting binding of the antibody.
Dependencies are inferred from the claim text.