Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis
AssigneeWisconsin Alumni Research Foundation
InventorsRobert I. DeMars, Seon-Kyeong Kim
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Abstract
Disclosed herein are short peptides from the major outer membrane protein of Chlamydia trachomatis serovar E. These fragments activate cytotoxic T-lymphocytes (CD8+). Thus, the fragments, as well as DNA coding for them, are intended for use in vaccination of humans. Also, they are useful in connection with diagnostic tests.
Claims7
A peptide of 9 to 10 amino acid residues that is separate from a Chlamydia trachomatis bacterial cell and a human cell, the peptide being capable of activating cytotoxic T-lymphocytes, the peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, SEQ ID NO:
- 5, and SEQ ID NO:
- 6, wherein the peptide does not have more than 10 amino acid residues.
Dependencies are inferred from the claim text.