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US 6,191,202 B1Granted
Cyanoacrylate adhesive compositions
AssigneeMedLogic Global Corporation
InventorsRichard J. Greff, Patrick J. Tighe, Michael M. Byram, Leonard V. Barley
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Abstract
Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably an acyl trialkyl citrate wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms), and SO2 as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.
Claims9
An alkyl cyanoacrylate composition which comprises:
- (a) from about 75 to about 82 weight percent of an alkyl cyanoacrylate based on the entire weight of the composition;
- (b) from about 50 to about 500 parts per million SO2, based on the entire weight of the composition, as a polymerization inhibitor;
- and
- (c) from about 18 to about 25 percent by weight, based on the entire weight of the composition, of an acyl trialkyl citrate wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms
- wherein the alkyl cyanoacrylate, in monomeric form, is represented by formula I:
- where R is alkyl of 2 to 10 carbon atoms.
3 more elements
An alkyl cyanoacrylate composition which comprises
- (a) from about 75 to about 80 weight percent of a cyanoacrylate selected from the group consisting of n-butyl cyanoacrylate and octyl cyanoacrylate based on the entire weight of the composition;
- (b) from about 50 to about 500 parts per million SO2, based on the entire weight of the composition, as a polymerization inhibitor;
- and
- (c) from about 20 to about 25 percent by weight of an acyl trialkyl citrate such that the alkyl cyanoacrylate composition is both durable and flexible when applied to the skin wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms based on the entire weight of the composition.
1 more element
Dependencies are inferred from the claim text.