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US 6,191,151 B1Granted
Therapy for herpes neurological viral conditions utilizing 1,4-dihydropyridine calcium channel blockers
OwnerHoward M. Zikinventor
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OwnerHoward M. Zikinventor
Estimating the term…
A therapy for Bells Palsy in mammals is proposed that rests on a causal hypothesis involving both endothelin and the herpes virus, particularly the herpes simplex virus for Bell's Palsy. Similarly, the same therapy would apply to Ramsay Hunt, but in this case the herpes zoster virus would be involved in the causal hypothesis. Other herpes viral related conditions are also suggested to be amenable such as herpes simplex encephalitis. The therapy uses therapeutically effective doses of calcium channel blockers that are of the 1,4-dihydropyridine derivative class, such as felodipine but also including nifedidine, nimodipine, nisodipine or alenodipine. The treatment is proposed as continuing up to the tenth day of progression, but to be started as early as possible. Acyclovir or other herpes antagonists such as famciclovir may also be administered in therapeutically effective dosages.
A method for the treatment of a patient having Bell's Palsy comprising dilating small arterioles in the patient's fallopian aqueduct to supply circulation to the 7th and other cranial nerve by administering to the patient therapeutically effective dosages of a 1,4 dihydropyridine calcium channel blocker.
A method for the treatment of a patient having Bell's Palsy comprising dilating small arterioles in the patient's fallopian aqueduct to supply circulation to the 7th and other cranial nerve by administering to the patient therapeutically effective dosages of a 1,4 dihydropyridine calcium channel blocker, wherein blood and oxygen flow to the seventh cranial nerve is enhanced.
A method for the treatment of a patient having Ramsay Hunt or other herpes neurological conditions comprising administering to the patient therapeutically effective dosages of a 1,4-dihydropyridine calcium channel blocker.
A method for the treatment of a patient having Ramsay Hunt or other herpes neurological condition comprising administering to the patient therapeutically effective dosages of a 1,4-dihydropyridine calcium channel blocker to enhance blood and oxygen flow to the seventh cranial nerve.
A method for enhancing blood circulation to the seventh cranial nerve comprising impairing endothelin's mechanism for generating vasoconstriction by the administration of a 1,4-dihydropyridine calcium channel blocker.
Dependencies are inferred from the claim text.