Aroyl aminoacyl pyrroles for use in the treatment of neuropathic pain

A method for the treatment of neuropathic pain comprising the step of administering to a mammal suffering from such condition an effective amount, in a pharmaceutically acceptable carrier, of an active compound of the formula:

• wherein,
• A is
• n is an integer from 1 to 5;
• R1 is selected from the group consisting of H and C1-4alkyl;
• R2 and R3 are selected from the group consisting of H and C1-4alkyl;
• R4 and R5 are independently selected from the group consisting of H, C1-4alkyl, phenyl C1-4 alkyl and substituted phenyl C1-4 alkyl where the substituent is on phenyl and selected from the group consisting of methyl and methoxy, or in the alternative, are fused and together with said nitrogen form a heterocyclic ring selected from the group consisting of 4-[bis(4-fluorophenyl)methylene]-piperidin-1-yl, 1,2,3,4-tetrahydro-6,7-dimethoxy-isoquinolin-2-yl,
• wherein Y is S or O, x is 3 to 7 and R7 is selected from the group consisting of methyl and hydroxymethyl;
• and
• R6 is selected from the group consisting of halo, C1-4 alkyl, C1-4 alkoxy, hydroxy, nitro, amino, C1-4 acylamino, cyano, trihaloC1-4alkyl, C1-4alkylsulfonyl, C1-4alkylsulfinyl, and C1-4 acyl,
• including pharmaceutically acceptable acid addition salts thereof.