Phenanthridines
AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorBeate Gutterer
Life of this patent
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Abstract
Compounds of formula (I), where R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings given in the description, are new active bronchial therapeutic agents.
Claims12
A compound of the formula I
- in which
- R1 is hydroxy, 1-4C-alkoxy, 3-7C-cycloalkoxy or 3-7C-cycloalkylmethoxy or 1-4C-alkoxy which is completely or partially substituted by fluorine,
- R2 is hydroxy, 1-4C-alkoxy, 3-7C-cycloalkoxy or 3-7C-cycloalkylmethoxy or 1-4C-alkoxy which is completely or partially substituted by fluorine,
- or in which
- R1 and R2 together are a 1-2C-alkylenedioxy group,
- R3 is hydrogen or 1-4C-alkyl,
- R31 is hydrogen or 1-4C-alkyl,
- or in which
- R3 and R31 together are a 1-4C-alkylene group,
- R4 is hydrogen or 1-4C-alkyl,
- R5 is hydrogen
- R51 is hydrogen,
- or in which
- R5 and R51 together are an additional bond,
- R6 is a phenyl radical which is substituted by R7, where
- R7 is COOR71 or CON(R72)R73 and R71 is hydrogen, 1-7C-alkyl, 3-7C-cycloalkyl or 3-7C-cycloalkylmethyl and R72 and R73 independently of one another are each hydrogen, 1-7C-alkyl, 3-7C-cycloalkyl or 3-7C-cycloalkylmethyl,
- or a salt of this compound.
A pharmaceutical composition comprising an effective amount of a compound as claimed in claim 10 or a pharmaceutically-acceptable salt thereof, and a suitable pharmaceutical auxiliary or excipient.
In a method for compounding a pharmaceutical composition which comprises combining an active ingredient for treating a respiratory disease with a suitable pharmaceutical auxiliary or excipient, the improvement wherein the active ingredient is a compound as claimed in claim 10, or a pharmaceutically-acceptable salt thereof.
Dependencies are inferred from the claim text.