Chicken interleukin-15 and uses thereof
AssigneeWayne State University
InventorsRoy S. Sundick, Lily A. Jones, David I. Smith
Life of this patent
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Abstract
The present invention pertains to isolated DNA encoding avian interleukin-15 and to purified interleukin-15 polypeptides.
Claims5
An isolated and purified DNA sequence encoding avian interleukin-15, wherein said interleukin-15 has a molecular weight of about 14,000 daltons, an isoelectric point of about 6.57, a net charge of −2, a hydrophilicity index of 0.278, and has the ability to stimulate mitogen-activated avian T cells.
An isolated and purified DNA comprising a sequence selected from the group consisting of the nucleotide sequence set forth in SEQ ID NO:
- 1 and sequence-conservative variants thereof, wherein the variants encode an avian interleukin-15 polypeptide having an isoelectric point of about 6.57, a net charge of −2, a hydrophilicity index of 0.278, and the ability to stimulate mitogen-activated avian T cells.
An isolated and purified DNA comprising a sequence encoding the amino acid sequence set forth in SEQ ID NO:2.
Dependencies are inferred from the claim text.