Process for making riboflavin glucoside
AssigneeRoche Vitamins Inc.
InventorsTatsuo Hoshino, Setsuko Masuda
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Abstract
A process for producing riboflavin glucoside comprises cultivating a microorganism belonging to the genus Bacillus, such as Bacillus brevis, Bacillus cereus, Bacillus circulans, Bacillus coagulans, Bacillus licheniformis, Bacillus megaterium, Bacillus pumilus or Bacillus subtilis, which is capable of producing riboflavin glucosides, in an aqueous medium containing a starch under aerobic conditions. Amongst the preferred strains are Bacillus subtilis RB50::[pRF69]60Ade+ and Bacillus subtilis RB50::[pRF69]60[pRF93]120Ade+. The so-produced riboflavin glucoside can be used as a more soluble substitute for riboflavin to prepare clear drinks and injection solutions.
Claims14
A process for producing a riboflavin glucoside, which comprises cultivating a microorganism having amylase activity and belonging to the genus Bacillus in an aqueous nutrient culture medium containing a starch under aerobic conditions, and recovering the riboflavin glucoside produced by the microorganism, wherein production of the riboflavin glucoside by the microorganism does not require exogenous riboflavin.
Dependencies are inferred from the claim text.