Fusion protein containing HMFG Epitop E (S)
AssigneeCancer Research Fund of Contra Costa
InventorsRoberto L. Ceriani, Jerry A. Peterson, David J. Larocca
Life of this patent
Estimating the term…
Abstract
A fusion protein comprises a sequence of amino acids which binds antibodies specific to the human milk fat globule (HMFG) differentiation antigens. Specific amino acid sequences are provided, and a fusion protein may be used as an immunogen and for diagnostic purposes.
Claims23
A fusion protein comprising a first peptide comprising an amino acid sequence or 1-10,000 repeats of an amino acid sequence, wherein said amino acid sequence is selected from the group consisting of SEQ. ID NO:4, SEQ. ID NO:6, SEQ. ID NO:7, SEQ. ID NO:8, SEQ. ID NO:9, SEQ. ID NO:10, SEQ. ID NO:12, SEQ. ID NO:13, SEQ. ID NO:14, SEQ. ID NO:15, SEQ. ID NO:16, SEQ. ID NO:17, SEQ. ID NO:18, SEQ. ID NO:19, SEQ. ID NO:20, SEQ. ID NO:21, SEQ. ID NO:22, SEQ. ID NO:23, SEQ. ID NO:24, SEQ. ID NO:25, SEQ. ID NO:26, SEQ. ID NO:27, SEQ. ID NO:28, SEQ. ID NO:29, SEQ. ID NO:30, SEQ. ID NO:31, SEQ. ID NO:32, and SEQ. ID NO:33;
- and a second peptide of at least 3 amino acids, which substantially fail to bind to human milk fat globule (HMFG) specific antibody;
- the fusion protein being at least 6 amino acids long.
Dependencies are inferred from the claim text.