Pharmaceutical methods of delivering folic acid
AssigneeOrtho-McNeil Pharamceutical, Inc.
InventorsMichael E. Kafrissen, Godfrey Oakley
Life of this patent
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Abstract
This invention provides folic acid-containing pharmaceutical compositions comprising either an oral contraceptive or a hormone replacement composition. This invention also provides methods of administering folic acid to a subject using the instant pharmaceutical compositions. Finally, this invention provides a drug delivery system useful for administering the instant pharmaceutical compositions.
Claims8
A method of administering folic acid to a subject for whom a hormonal replacement composition is indicated for treating or preventing a menopausal condition, which comprises administering to the subject a pharmaceutical composition, wherein
- (a) the pharmaceutical composition comprises a hormonal replacement composition for treating or preventing a menopausal condition in a subject, and folic acid in an amount sufficient to treat or prevent a disorder which (i) afflicts subjects for whom the hormonal replacement composition is indicated at a higher-than-normal incidence, and (ii) is treatable or preventable by folic acid administration, and
- (b) the subject is from a population whose members are afflicted with, or predisposed to become afflicted with, a disorder at a higher-than-normal incidence, the disorder being treatable or preventable by folic acid administration.
A method of administering folic acid to a subject for whom a hormonal replacement composition is indicated for treating or preventing a hypogonadal condition, which comprises administering to the subject a pharmaceutical composition, wherein
- (a) the pharmaceutical composition comprises a hormonal replacement composition for treating or preventing a hypogonadal condition in a subject, and folic acid in an amount sufficient to treat or prevent a disorder which (i) afflicts subjects for whom the hormonal replacement composition is indicated at a higher-than-normal incidence, and (ii) is treatable or preventable by folic acid administration, and
- (b) the subject is from a population whose members are afflicted with, or predisposed to become afflicted with, a disorder at a higher-than-normal incidence, the disorder being treatable or preventable by folic acid administration.
A method of administering folic acid to a subject for whom an oral contraceptive is indicated for preventing pregnancy, which comprises administering to the subject a pharmaceutical composition, wherein
- (a) the pharmaceutical composition comprises an oral contraceptive for preventing pregnancy in a subject, and folic acid in an amount sufficient to treat or prevent a teratogenic or cardiovascular disorder which (i) afflicts subjects for whom the oral contraceptive is indicated at a higher-than-normal incidence, and (ii) is treatable or preventable by folic acid administration, and
- (b) the subject is from a population whose members are afflicted with, or predisposed to become afflicted with, a teratogenic or cardiovascular disorder at a higher-than-normal incidence, the disorder being treatable or preventable by folic acid administration.
Dependencies are inferred from the claim text.