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US 6,190,351 B1Granted
Nutritional support system
AssigneeAlza Corporation
InventorsRichard G. Weyers, Atul D. Ayer, Brenda J. Pollock, Brian L. Barclay, Ernest S. Quan
Life of this patent
Estimating the term…
Abstract
A nutritional system is disclosed, for delivering a colorant dye to a nutritional fluid that flows through the nutritional system.
Claims5
A delivery system for adding a dye to a nutritional formulation, wherein the delivery system comprises:
- a core comprising 20 to 70 wt % of a dye, 10 to 40 wt % of a carbohydrate, 2 to 30 wt % of a hydroxypropylalkylcellulose of 9,200 to 125,000 molecular weight, 5 to 25 wt % of an osmagent, 0.5 to 5 wt % of a lubricant, and 0.5 to 12 wt % of a hydroxyalkylcellulose of 30,000 to 50,000 molecular weight;
- a wall that surrounds the core and comprises 40 to 90 wt % of a member selected from the group consisting of a cellulose ester, cellulose ether and cellulose esterether, 5 to 25 wt % of a poly(vinyl pyrrolidone) of 15,000 to 75,000 molecular weight, and 0.5 to 8 wt % of a polyethylene glycol of 2,000 to 5,000 molecular weight;
- an overcoat on the wall comprising 10 to 30 wt % of a dye, 35 to 75 wt % of a carbohydrate, 4 to 18 wt % of a hydroxypropylalkylcellulose of 9,200 to 75,000 molecular weight, and 5 to 20 wt % of a polyethylene glycol of 2,000 to 5,000 molecular weight;
- an exit means in the delivery system, and wherein the overcoat delivers the dye immediately and the core dye delivers the dye over a prolonged period of time up to 25 hours.
1 more element
A nutritional system comprising:
- 255.0 mg of a pharmaceutically acceptable dye, 147.9 mg of a carbohydrate, 15.3 mg of a hydroxypropylalkylcellulose, 61.2 mg of an osmagent, 5.1 mg of a lubricant, and 25.5 mg of a hydroxyalkylcellulose;
- a wall comprising 20.8 mg of a cellulose polymer, 4.2 mg wt % of a poly(vinyl pyrrolidone), and 1.0 mg of a lubricant;
- an overcoat comprising 24.8 mg of a carbohydrate, 4.5 mg of a hydroxypropylalkylcellulose, 6.8 mg of polyethylene glycol, and 9.0 mg of a non-toxic dye;
- and an exit in the delivery system.
1 more element
A nutritional system comprising:
- (a) a reservoir comprising a nutritional fluid formulation;
- (b) a drip chamber in communication with the reservoir;
- and
- (c) a delivery device in the drip chamber, which delivery device comprises:
- 255 mg of a pharmaceutically acceptable dye, 147.9 mg of a carbohydrate, 15.3 mg of a hydroxypropylalkylcellulose, 61.2 mg of an osmagent, 5.1 mg of a lubricant and 25.5 mg of a hydroxyalkylcellulose;
- a wall comprising 20.8 mg of a cellulose polymer, 4.2 mg of a poly(vinyl pyrrolidone) and 0.1 mg of a lubricant;
- and an exit in the delivery system.
4 more elements
Dependencies are inferred from the claim text.