Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue

An apparatus for processing biopotentials sensed in myocardial tissue at first, second, and third signal sensor sites, the apparatus comprising:

• first and second signal processing channels;
• a processing element coupled to the first and second signal processing channels, the processing element comprising
• a first controller for coupling signals sensed at the first and second signal sensor sites to the first and second signal processing channels during a first time interval to record a first set of signals, the first set of signals comprising a plurality of biopotentials sensed in myocardial tissue;
• a second controller for coupling signals sensed at the first and third signal sensor sites to the first and second signal processing channels during a second time interval different than the first time interval to record a second set of signals, the second set of signals comprising a plurality of biopotentials sensed in myocardial tissue, at least one of the biopotentials in the first set of signals being sensed in the first time interval and not in the second time interval, and at least one of the biopotentials in the second set of signals being sensed in the-second time interval and not in the first time interval;
• and
• a third controller for time aligning the first and second sets of signals by using biopotentials sensed by the first set of signals to create a composite set of signals comprising the biopotentials sensed at the first, second, and third signal sensor sites arranged for analysis as if all biopotentials were recorded during a common time interval, whereby the composite set provides a diagnostic indicator.

A method for generating a composite signal derived from biopotentials sensed in myocardial tissue comprising:

• inputting a first set of signals comprising biopotentials sensed at a first group of tissue sites during a first time interval;
• inputting a second set of signals comprising biopotentials sensed at a second group of tissue sites during a second time interval sequentially after the first time interval, wherein at least one of the biopotentials sensed as part of the first set of signals is not sensed as part of the second set of signals, and at least one of the biopotentials sensed as part of the second set of signals is not sensed as part of the first set of signals;
• and
• time aligning the first and second sets of signals using biopotentials sensed at the same site as part of both the first and second sets of signals, thereby generating the composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby the composite signal provides a diagnostic indicator.