Tubby 2 polypeptides
AssigneeSmithKline Beecham Corporation
InventorsJonathan Alexander Terrett, Tania Tamson Testa, Israel Simon Gloger, Stephen A. Hughes, Trudy Rachel Doe
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Abstract
Tubby 2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Tubby 2 polypeptides and polynucleotides in the design of protocols for the treatment of diabetes, obesity, and atherosclerosis, among others, and diagnostic assays for such conditions.
Claims14
An isolated polypeptide comprising an amino acid sequence which has at least 70% identity to the amino acid sequence of SEQ ID NO:2 over the entire length of SEQ ID NO:2, said identity being calculated using FASTA wherein the two sequences are aligned so that highest order match is obtained.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:4.
An isolated polypeptide comprising at least 50 contiguous amino acids from the amino acid sequence set forth in SEQ ID NO:2.
An isolated polypeptide comprising at least 50 contiguous amino acids from the amino acid sequence set forth in SEQ ID NO:4.
Dependencies are inferred from the claim text.