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US 6,187,803 B1Granted
Drug preparation for oral administration
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsHaruo Yoshii, Yuriko Yamazaki
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AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsHaruo Yoshii, Yuriko Yamazaki
Estimating the term…
A drug preparation for oral administration containing histamine-added immunoglobulin as an effective component may be used for prevention or treatment of allergic diseases such as bronchial asthma, allergic rhinitis, vasomotor rhinitis, urticaria, chronic eczema and atopic dermatitis; autoimmune diseases such as multiple sclerosis, chronic rheumatoid arthritis and systemic lupus erythematodes; various immunodeficiency syndromes; and also eosinophilia or various inflammatory diseases caused by infectious diseases, parasitic diseases, diseases of respiratory organs, autoimmune diseases, and malignant tumors. The drug preparation which can be administered orally can be taken by patients easier than an injectable preparation without loss of effectiveness. Therefore, the drug preparation for oral administration of the present invention is practical and highly useful.
A method for the treatment of an allergic disease, autoimmune disease, immunodeficiency syndrome, inflammatory disease, or eosinophilia comprising orally administering to a patient in need of such treatment an orally ingestible, pharmaceutical composition comprising a pharmaceutically effective amount of a histamine-added immunoglobulin and a pharmaceutically acceptable carrier.
A pharmaceutical composition for oral administration comprising histamine-added immunoglobulin as an effective component and a pharmaceutically acceptable carrier, said histamine-added immunoglobulin being obtained by admixing an immunoglobulin component and a histamine component in a weight ratio of about 1 mg to about 200 mg of the immunoglobulin component to about 0.01 μg to about 2 μg of the histamine component, said pharmaceutical composition being in the form of a tablet, or capsule.
A pharmaceutical composition for oral administration consisting essentially of histamine-added immunoglobulin as an effective component and a pharmaceutically acceptable carrier, said histamine-added immunoglobulin being obtained by admixing an immunoglobulin component and a histamine component in a weight ratio of about 1 mg to about 200 mg of the immunoglobulin component to about 0.01 μg to about 2 μg of the histamine component, said pharmaceutical composition being in the form of a tablet, or capsule.
Dependencies are inferred from the claim text.