Method for the prevention and treatment of mastitis
AssigneeNovartis Animal Health US, Inc.
InventorsBruno Suri, Catherine Georges, John Edmondson Peel
Life of this patent
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Abstract
A method for treating or preventing mastitis in mammals is disclosed. The method contemplates the intramammary injection or dipping the teat with micrococcin antibiotics, preferably micrococcin P1 or P2, which do not interfere with the production of cheese and yoghurt using milk from treated animals. Hydrophobic antibiotics such as micrococcin P1 or P2 can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis.
Claims9
A method of treating or preventing contagious mastitis caused by pathogens susceptible to micrococcin P1 or P2 in a mammal comprising administering to the mammal a therapeutically effective amount of micrococcin P1 or P2, wherein the milk obtained from the mammal after the administration of the micrococcin P1 or P2 is suitable for use in the production of cheese or yogurt.
A method for the prophylaxis of contagious mastitis in a mammal comprising administering to the mammal a therapeutically effective amount of micrococcin P1 or P2, wherein the milk obtained from the mammal after the administration of the micrococcin P1 or P2 is suitable for use in the production of cheese or yogurt.
A method for the preparation of micrococcin P1 or P2 comprising fermenting the bacterial species Staphylococcus sciuri according to standard techniques, sterilizing the whole fermentation broth, separating the bacterial cells from the fermentation broth, and extracting micrococcin P1 or P2 from the cells with methanol.
Dependencies are inferred from the claim text.