Kit for flushing medical devices and method of preparation
AssigneeBecton, Dickinson and Company
InventorsCharles J. Welle, Steven C. Felton, Mohammad A. Khan
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Abstract
A kit and for flushing a medical device a method of preparing the kit is disclosed. The kit includes a container containing a mixed solution a unit dose of a pharmacologically effective amount of an antimicrobial agent and a second agent. The mixed solution has been mixed in a carrier solution and lyophilized. The second agent is an anticoagulant, an antithrombotic agent or a chelating agent. The kit and method are useful for maintaining the patency of indwelling medical devices such as catheters and for preventing infections caused by bacterial growth in catheters.
Claims18
A kit for flushing a medical device comprising:
- a dry lyophilized unit dose of a pharmacologically effective amount of an antimicrobial agent and a second agent selected from the group consisting of an anticoagulant, an antithrombotic agent and a chelating agent.
A kit for flushing a medical device comprising a lyophilized unit dose of a pharmacologically effective amount of minocycline and EDTA mixed in a carrier solution.
A kit for flushing a catheter comprising:
- a lyophilized unit dose of mixture of at least about 9 mg of minocycline and at least about 90 mg of EDTA that has been mixed in a carrier solution;
- a second carrier solution for reconstituting the lyophilized unit dose;
- a container for mixing the second carrier solution and the lyophilized unit dose;
- and
- means for introducing the mixture of the lyophilized unit dose and the second carrier solution into the catheter.
A method of preparing a solution for flushing a catheter comprising:
- lyophilizing a mixture of a pharmacologically effective amount of minocycline and EDTA in a carrier solution;
- storing the lyophilized mixture in a container;
- and
- reconstituting the lyophilized mixture in a liquid.
A method for preparing a lyophilized solution for flushing a medical device comprising:
- mixing in a carrier solution an antimicrobial agent and a second agent selected from the group consisting of an anticoagulant, an antithrombotic agent and a chelating agent;
- and
- lyophilizing the mixture to provide a unit dose of the mixture which can be reconstituted in a second carrier solution.
Dependencies are inferred from the claim text.