Mometasone furoate suspensions for nebulization
AssigneeSchering Corporation
InventorsDavid Harris, Joel A. Sequeira, Imtiaz A. Chaudry
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Abstract
An aqueous nebulizer suspension contains water, mometasone furoate monohydrate, a nonionic surfactant, a soluble salt and optionally a pH buffer. The suspension may be prepared by ultrasonication or jet milling techniques.
Claims21
A nebulizer suspension consisting essentially of water, mometasone furoate monohydrate, a nonionic surfactant, about 0.2 to about 2 weight percent of sodium chloride or potassium chloride and, optionally, a pH buffer.
A process for producing a nebulizer suspension, comprising combining ingredients consisting essentially of water, mometasone furoate monohydrate, a nonionic surfactant, about 0.2 to about 2 weight percent of sodium chloride or potassium chloride and, optionally, a pH buffer and subjecting the combination to particle size reduction by ultrasonication or by jet milling.
Dependencies are inferred from the claim text.